Aster DM Healthcare Limited
Cheranelloor, Kochi, Kerala, India.
Tel: +91 484 66 99 999
Closest Railway Station
Cochin International Airport.
Dr. Vinod Kumar, Consultant, Aster Centre of Excellence in Nephrology & Urology
Chronic Kidney Disease (CKD) or chronic renal failure is a condition wherein there is a progressive loss in the kidney function. This may occur over a period of time, ranging from months to years. This condition, unlike acute kidney injury (temporary kidney failure that is reversible partially or completely) is permanent and irreversible.
Kidneys are our body’s filters. They purify blood and eject toxins through urine. So when they lose the ability to function, nitrogenous waste products and toxins gets accumulated in the body, resulting in symptoms and signs of CKD. Among these, the measurable indicators are urea and creatinine levels, which can be detected/ determined through specific blood tests.
Unfortunately, the number of patients with CKD is on the rise globally, with more around 5 to 10% of the world population affected by it. The numbers are increasing steadily also due to high incidence of lifestyle disorders like diabetes and hypertension, even in those below 40 years of age.
It is estimated that the age adjusted incidence rate of ESRD is 229/million population, with over 150,000 patients developing ESRD every year. Also, diabetes and hypertension account for two-thirds of the CKD cases.
Kerala, which has infamously been dubbed the diabetic capital of India, is now witnessing a steady rise in the number of patients with CKD progressing to ESRD and requiring dialysis or transplant.
Detecting CKD With Glomerular Filtration Rate (GFR)
GFR is the best and the most efficient way to determine the level of kidney function and the extent/ stage of kidney failure. GFR is calculated using a formula that involves a person’s age, gender, race and serum creatinine levels. A permanent, irreversible condition, CKD will invariably progress to End Stage Renal Disease (ESRD). A life-threatening condition, the only solution for ESRD is renal replacement therapy (RRT) or kidney transplant.
Risk Factors/ Causes of Chronic Kidney Disease
Kidneys can get damaged due to a wide range of reasons including:
Symptoms & Signs
Symptoms of CKD may not show/ be extremely subtle during early stages of chronic kidney disease. Symptoms may become apparent only after the kidney function is significantly impaired, which means irreversible damage. The symptoms of CKD include:
Management of CKD An irreversible condition, there are no treatment options for CKD. The only thing that can be done is management, which involves prevention or slowing down the progression of the disease. A Nephrologist will recommend the required treatment after detailed assessments and investigations. It is important to diagnose chronic kidney disease in its early stages to prevent further worsening of the condition. Those with high risk factors should get their kidney functions checked regularly. Preventing Progression Of CKD:
Treatment Options For ESRD: